The Cohoes Musical Hall, located in the Downtown Cohoes Historic District, is listed on the National Register of Historic Places. It was constructed in 1874 by two local businessmen and opened with a performance of Dion Boucicault's London Assurance. Over the years, the Music Hall has had performers including Sarah Bernhardt, Buffalo Bill Cody, George M. Cohan, Jimmy Durante, Lillian Russell, John Phillip Sousa, and Cohoes native at the time, Eva Tanguay who have played at the Music Hall.
In recent years, the Cohoes Music Hall has been a core in the arts community and has been a staple in cultural and economic development within the community. Since 2002 it has been the home of C-R Productions, which is committed to revitalizing the theatre. Residents and visitors from all over the capital region visit the music hall to see one of their many successful shows including Chicago and Miss Saigon. In addition, the Music Hall offers summer programs with an educational benefit for students and kids as well as a program partnered with the Center for Disability Services. Additionally, the street-level offices serve as the City of Cohoes’ Visitor Center with displays on the history of the textile industry in the city and information about historic sites and other local attractions.